HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylamine → HCID 53640330, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | Ethyl isovalerate | HCID 7945 | — |
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | HCID 53640330 | HCID 53640330 | 44% |
Reaction Steps
Nicotinic chloride hydrochloride (0.9 g), isovaleric acid ethyl ester (2.3 ml), diisopropylamine (2.1 ml) and butyllithium (1.6M hexane solution, 9.4 ml) were subjected to reaction and post-treatment in a similar manner to that described in Reference example 8(a) to obtain the title compound (0.78 g, 44%) as a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06005116 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-c04b94fa7a434511b646529498601752 |
| Source note | uspto-grants-1999_12 |