HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetylbenzoic acid → 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetylbenzoic acid | HCID 68474 | — |
| Reactant | 1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene | HCID 22007332 | — |
| Solvent | Ethylene Glycol | HCID 174 | — |
| Product | 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene | HCID 22007441 | 87.5% |
Reaction Steps
1-(2-Hydrazino-4-pyridyl)-3-hydroxymethyl-6,7-diethoxynaphthalene (177 mg), 1-carboxy-2-methylcarbonylbenzene (86 mg) and ethylene glycol (1 ml) are treated in the same manner as in Example 104-(3) to give 1-{2-(4-methyl-1(2H)-phthalazinon-2-yl)-4-pyridyl}-3-hydroxymethyl-6,7-diethoxynaphthalene (211 mg), which is listed in Table 14.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06005106 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-17557410309f4bf781b19e37e0451b54 |
| Source note | uspto-grants-1999_12 |