Acetic Acid → 3-[Bis(phenylmethyl)amino]-4-hydroxy-6-phenyl-2H-pyran-2-one

Participants

Reaction Steps

The title compound was prepared by Method D using 3-amino-4-hydroxy-6-phenyl-2H-pyran-2-one hydrochloride (0.150 g, 0.626 mmol), 1% acetic acid in dimethylformamide (7 mL), benzaldehyde (0.133 mL, 1.33 mmol), sodium cyanoborohydride (0.083 g, 1.31 mmol). m.p. 130-135° C.; 1H NMR (400 MHz, DMSO-d6) δ4.26 (s, 4 H), 6.44 (s, 1 H), 7.24 (m, 6 H), 7.44 (m, 7 H), 7.69 (m, 2 H).

Provenance & Evidence