3-Acetylpyridine → HCID 54681466, compound

HRID 613118Notes

Reaction equation

HRID 613118 reaction equation
[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].[C:10]1([CH2:16][S:17][CH:18]([C:22](O)=[O:23])[C:19](O)=[O:20])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[OH:23][C:22]1[CH:2]=[C:1]([C:4]2[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=2)[O:3][C:19](=[O:20])[C:18]=1[S:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 95893-AcetylpyridineHCID 19596125[(Phenylmethyl)thio]propanedioic acid

Product 1

HCID 54681466HCID 54681466, compound

Procedure

The title compound was prepared from the condensation of the trimethylsilyl enol ether of 3-acetyl pyridine and diethyl ester of [(phenylmethyl)thio]propanedioic acid following the same procedure outlined in Method A; m.p. 183-184° C. NMR (DMSO-d6) δ4.02 (s, 2 H), 6.83 (s, 1 H), 7.20 (m, 1 H), 7.26 (d, 4 H), 7.55 (m, 1 H), 8.16 (m, 1 H), 8.69 (m, 1 H), 8.98 (d, 1 H).

Sources & evidence

ORD record
ord-87b6b38654e348fc81b37aaf3dd8fc62
Source dataset
uspto-grants-1999_12
Patent number
US06005103

Reaction notes

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