1-(Thiophen-3-yl)ethanone → HCID 54681325, compound

HRID 613120Notes

Reaction equation

HRID 613120 reaction equation
[C:1]([C:4]1[CH:8]=[CH:7][S:6][CH:5]=1)(=[O:3])[CH3:2].[C:9]1([CH2:15][S:16][CH:17]([C:21](O)=[O:22])[C:18](O)=[O:19])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[OH:22][C:21]1[CH:2]=[C:1]([C:4]2[CH:8]=[CH:7][S:6][CH:5]=2)[O:3][C:18](=[O:19])[C:17]=1[S:16][CH2:15][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 151161-(Thiophen-3-yl)ethanoneHCID 19596125[(Phenylmethyl)thio]propanedioic acid

Product 1

HCID 54681325HCID 54681325, compound

Procedure

The title compound was prepared from the condensation of the trimethylsilyl enol ether of 3-acetylthiophene and the diethyl ester of [(phenylmethyl)thio]propanedioic acid following the same procedure outlined in Method A; m.p. 150-151° C. NMR (DMSO-d6) δ3.98 (s, 2 H), 6.58 (s, 1 H), 7.20 (m, 5 H), 7.48 (m, 1 H), 7.72 (m, 1 H), 8.13 (d, 1 H).

Sources & evidence

ORD record
ord-ce61a2dc46a443f889e6c0b5bf49cf2e
Source dataset
uspto-grants-1999_12
Patent number
US06005103

Reaction notes

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