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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 613232Generated: October 29, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/613232

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step b, the acid chloride (7) is amidated with morpholine (8) by techniques and procedures well known and appreciated by one of ordinary skill in the art to give the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester (9).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06008196
Source datasetuspto-grants-1999_12
ORD IDord-2540c0e4672b4b209913cf89c5c255a2
Source noteuspto-grants-1999_12