HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-(Morpholine-4-carbonyl)nicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-(Morpholine-4-carbonyl)nicotinic acid, t-butyl ester | HCID 10085718 | — |
| Solvent | Nitromethane | HCID 6375 | — |
| Product | 6-(Morpholine-4-carbonyl)nicotinic acid | HCID 10105514 | — |
Reaction Steps
In step c, the t-butyl ester functionality of (12) is hydrolyzed, with for example, HCl in nitromethane, to give the corresponding, 6-(morpholine-4-carbonyl)nicotinic acid (13).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06008196 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-e7feb12be74c4881a2e19dc4bdb74148 |
| Source note | uspto-grants-1999_12 |