Sodium Hydroxide → HCID 15888084, compound

Participants

Reaction Steps

A mixture of ethyl (±)-10,11-dihydro-3-[3-(2-pyridylamino)-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate (1 mmole) and 1.0 N NaOH (1.2 mmole) in absolute EtOH (10 mL) is warmed in an oil bath set at 50° C. When the reaction is complete, the solvents are removed on the rotavap and the residue is purified by ODS chromatography. Concentration and lyophilization afford the title compound.

Provenance & Evidence