Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester → HCID 19592450, compound

Participants

Reaction Steps

A mixture of 3-formyl-8-nitroquinoline (65 mg) and ethyl (triphenylphosphoranilidene)acetate (123 mg) in dichloromethane (3 ml) was stirred for 2 hours at ambient temperature. The mixture was concentrated in vacuo, and the residue was purified by column chromatography on silica gel (ethyl acetate-n-hexane) to give 3-((E)-2-ethoxycarbonylvinyl)-8-nitroquinoline (92 mg).

Provenance & Evidence