HCID 19592667, compound → HCID 19592398, compound

Participants

Reaction Steps

A mixture of 8-(2,6-dichlorobenzoylamino)-3-((E)-2-ethoxycarbonylvinyl)quinoline (40 mg) and platinum (IV) oxide (5 mg) in dioxane (1 ml) was stirred for 3 hours at ambient temperature under hydrogen atmosphere. Insoluble material was filtered off and the filtrate was concentrated in vacuo. The residue was purified by preparative thin layer chromatography (ethyl acetate-n-hexane) to give 8-(2,6-dichlorobenzoylamino)-3-(2-ethoxycarbonylethyl)quinoline (16 mg).

Provenance & Evidence