HCID 19592319, compound → HCID 19592928, compound

Participants

Reaction Steps

A solution of 8-(2,6-dichlorobenzoylamino)-4-[2-(3-pyridinecarboxamido)phenylamino]quinoline (150 mg) in acetic acid was refluxed for 60 hours. After cooling, the mixture was concentrated in vacuo and diluted with ethyl acetate. The solution was washed with saturated sodium bicarbonate solution, dried over magnesium sulfate and evaporated in vacuo. The residue was crystallized from acetonitrile and collected by filtration to give 8-(2,6-dichlorobenzoylamino)-4-[2-(3-pyridyl)-1H-benzimidazol-1-yl]quinoline (136 mg).

Provenance & Evidence