1,3-Butadiene → HCID 53851086, compound
Reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[CH2:8]=[CH:9][CH:10]=[CH2:11]>>[CH2:1]([C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1)[CH2:8][CH:9]=[CH:10][CH3:11]Participants
3
Conditions
- Temperature
- 140 °C
Procedure
220 g of 4-methylpyridine and 1.0 g of solid base A were fed into a 1000 ml autoclave equipped with an electromagnetic stirrer under an atmosphere of nitrogen, and then heated to 140° C. with stirring at 700 r.p.m. subsequently, 16.5 g of butadiene was added to the mixture in 1 hour. After the reaction, the autoclave was cooled and the catalyst was removed by filtration. The reaction solution was analyzed by gas chromatography. 4-(3-pentenyl)pyridine was obtained in a 86% yield based on 4-methypyridine consumed.
Workup
- customequipped with an electromagnetic stirrer under an atmosphere of nitrogen
- customAfter the reaction
- temperaturethe autoclave was cooled
- customthe catalyst was removed by filtration
Sources & evidence
- ORD record
- ord-1fbfe443915045aca45a27cc954ee1bb
- Source dataset
- uspto-grants-1999_12
- Patent number
- US06008364
Reaction notes
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