HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium cyanoborohydride → AR-C-89855 hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | Methyl 3-[2-[2-(4-methylphenyl)ethoxy]ethylaminosulphonyl]propanoate | HCID 18779034 | — |
| Reactant | Diisobutylaluminumhydride | HCID 21225700 | — |
| Reactant | 4-Hydroxy-7-(2-aminoethyl)-1,3-benzothiazol-2(3H)-one hydrochloride | HCID 60207553 | — |
| Product | AR-C-89855 hydrochloride | HCID 10218133 | 5% |
Reaction Steps
The title compound (0.2 g) was prepared according to the procedure in example 5 part e using methyl 3-[2-[2-(4-methylphenyl)ethoxy]ethylaminosulphonyl]propanoate (2.49 g), diisobutylaluminiumhydride (1.5M in toluene, 7.5 ml), 7-(2-aminoethyl)-4-hydroxy-1,3-benzothiazol-2(3H)-one hydrochloride (2.2 g) and sodium cyanoborohydride (0.48 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06008365 |
| Source dataset | uspto-grants-1999_12 |
| ORD ID | ord-949c7177bbda4e588388024bff27b28f |
| Source note | uspto-grants-1999_12 |