HRID613938

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(CC(C(=O)N[C@H]1CCCCNC1=O)N1C=CN(c2ccc(-c3ccccc3)cc2)C1)OCc1ccccc1

HCID53846884

未命名化合物

PRODUCTS

生成物

结构：O=C(O)CC(C(=O)N[C@H]1CCCCNC1=O)N1C=CN(c2ccc(-c3ccccc3)cc2)C1

HCID18341321

未命名化合物

收率 94%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

According to the procedure described in Example 1(a), a suspension of 3(RS)-(3-biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl)succinamic acid benzyl ester in EtOH was hydrogenolyzed after 90 minutes to provide 779 mg (94%) of 3(RS)-(3-biphenyl-4-yl-1H-imidazol-1-yl)-N-(hexahydroazepin-2-on-3(S)-yl)succinamic acid as a solid. FABMS: 447 (C25H27N4O4 ; M+H+).