Sodium Hydroxide → 2,3-Dihydro-6-methoxy-2-methyl-4-benzofurancarboxylic acid

HRID 614002Notes

Reaction equation

HRID 614002 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[C:7]([O:15][CH3:16])[CH:8]=[C:9]2[O:13][CH:12]([CH3:14])[CH2:11][C:10]=12)=[O:4].[OH-].[Na+]>O.C(O)C>[CH3:16][O:15][C:7]1[CH:8]=[C:9]2[O:13][CH:12]([CH3:14])[CH2:11][C:10]2=[C:5]([C:3]([OH:4])=[O:2])[CH:6]=1

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 543897576-Methoxy-2-methyl-2,3-dihydro-benzofuran-4-carboxylic acid methyl ester

Product 1

HCID 213298152,3-Dihydro-6-methoxy-2-methyl-4-benzofurancarboxylic acid

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

To a stirred mixture of 158 grams of 2,3-dihydro-6-methoxy-2-methyl-4-benzofurancarboxylic acid methyl ester and 88.5 grams of flake sodium hydroxide in 320 cc of water, ethanol is gradually added until a clear solution is obtained.

Workup

  1. additionis gradually added until a clear solution
  2. customis obtained

Sources & evidence

ORD record
ord-6a1255367ce544b7881ca3a135d9569a
Source dataset
uspto-grants-1979_03
Patent number
US04143055

Reaction notes

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