HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → N-(2,3-dihydro-6-methoxy-2-methyl-4-benzofuranyl)propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | 2,3-Dihydro-6-methoxy-2-methyl-4-benzofuranamine | HCID 21329811 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-(2,3-dihydro-6-methoxy-2-methyl-4-benzofuranyl)propanamide | HCID 21329827 | — |
Reaction Steps
The compound of the title is prepared according to the procedure described in Example 10 by reacting the starting 2,3-dihydro-6-methoxy-2-methyl-4-benzofuranamine with propionyl chloride instead of ethylchlorocarbonate. M.p. 101°-02° C. (from ethyl ether). Yield 44 grams (75 percent of theoretical).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04143055 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-46b5e0f9f9834d24b4b688b36062108c |
| Source note | uspto-grants-1979_03 |