N-Methylaniline → HCID 21329844, compound

Participants

Reaction Steps

A solution of 2.3 g of m-trifluoromethyl-α,α-dimethylbenzyl isocyanate in 5 ml of benzene was added to 1.1 g of N-methylaniline in 5 ml of benzene and the mixture was heated under reflux for 2 hours. After allowing the reaction mixture to cool, the mixture was washed successively with 2N aqueous sodium hydroxide, 2N hydrochloric acid and water and dried over anhydrous sodium sulfate. The solvent was then removed by distillation and the resulting crystals were recrystallized from n-hexane to obtain 2.6 g of the title compound.

Provenance & Evidence