HCID 86736375, compound → HCID 86736376, compound

HRID 614084Notes

Reaction equation

HRID 614084 reaction equation
[CH:1]1([N:7]2[CH2:11][CH2:10][CH:9]([NH:12][C:13]([C:15]3[CH:26]=[CH:25][CH:24]=[CH:23][C:16]=3[NH:17][C:18](=[O:22])[C:19]([O-:21])=[O:20])=[O:14])[CH2:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Na+]>O>[CH:1]1([N:7]2[CH2:11][CH2:10][CH:9]([NH:12][C:13]([C:15]3[CH:26]=[CH:25][CH:24]=[CH:23][C:16]=3[NH:17][C:18](=[O:22])[C:19]([OH:21])=[O:20])=[O:14])[CH2:8]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 1

HCID 86736375HCID 86736375, compound

Product 1

HCID 86736376HCID 86736376, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The amorphous sodium salt from Example 5 was suspended in distilled water; the pH of the solution was 9.0. The stirred solution was cooled and acidified with dilute hydrochloric acid to pH 4 at which point maximum precipitation occurred. The precipitate was collected and air-dried to give 2.76 g. of product which melted at 268°-270° C.

Workup

  1. temperatureThe stirred solution was cooled
  2. customacidified with dilute hydrochloric acid to pH 4 at which point maximum precipitation
  3. customThe precipitate was collected
  4. customair-dried
  5. customto give 2.76 g

Sources & evidence

ORD record
ord-3cf319d95b034d4ea0858194a0e5a6af
Source dataset
uspto-grants-1979_03
Patent number
US04143150

Reaction notes

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