Sulfuryl chloride → HCID 12520012, compound

HRID 614219Notes

Reaction equation

HRID 614219 reaction equation
[CH2:1]([O:3][C:4]1[C:5]([C:9]([OH:11])=[O:10])=[CH:6][S:7][CH:8]=1)[CH3:2].S(Cl)([Cl:15])(=O)=O>C(Cl)(Cl)Cl>[Cl:15][C:8]1[S:7][CH:6]=[C:5]([C:9]([OH:11])=[O:10])[C:4]=1[O:3][CH2:1][CH3:2]

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 125200094-Ethoxythiophene-3-carboxylic acid

Product 1

HCID 12520012HCID 12520012, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A 15.45 g. portion of 4-ethoxy-3-thiophenecarboxylic acid is suspended in 30 ml. of chloroform. To this is added dropwise 8.1 ml. of sulfuryl chloride with stirring. The mixture is stirred for 30 minutes and the precipitate is collected, giving 5-chloro-4-ethoxy-3-thiophenecarboxylic acid.

Workup

  1. additionTo this is added dropwise 8.1 ml
  2. customthe precipitate is collected

Sources & evidence

ORD record
ord-deba59c1e81f4b71988914ee444f1ab1
Source dataset
uspto-grants-1979_03
Patent number
US04144235

Reaction notes

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