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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 614313Generated: October 30, 2026

N,N-Dimethylaminoethyl chloride hydrochloride → 2-(2-Dimethylaminoethylamino)-4-methyl-6-dimethylaminopyrimidine

https://huagongshe.com/reaction/614313

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethylaminoethyl chloride hydrochlorideHCID 11636816—
Reactant2-Acetamido-4-methyl-6-dimethylaminopyrimidineHCID 23349878—
Product2-(2-Dimethylaminoethylamino)-4-methyl-6-dimethylaminopyrimidineHCID 23349869—

Reaction Steps

Following the procedure of Example 1, Part A 2-acetamido-4-methyl-6-dimethylaminopyrimidine and 2-dimethylaminoethyl chloride hydrochloride, 2-(2-dimethylaminoethylamino)-4-methyl-6-dimethylaminopyrimidine is obtained with a boiling point of 120°-124° C. at 0.03 mm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04144338
Source datasetuspto-grants-1979_03
ORD IDord-23e583561aee441b8258bb4e9a426262
Source noteuspto-grants-1979_03