Triethylamine → HCID 23349877, compound

Participants

Reaction Steps

A solution of cyanogen bromide (15.9 g., 0.150 mole) in 75 ml of tetrahydrofuran is added to a solution of 2-(2-dimethylaminoethylamino)pyrazine (16.6 g., 0.1 mole) and triethylamine (20.9 g., 0.15 mole) in 100 ml of tetrahydrofuran. After 72 hours, dilute sodium hydroxide is added and the mixture is extracted with ether. The extracts are concentrated and the residue is distilled under reduced pressure. N-(2-Dimethylaminoethyl)-N-(2-pyrazinyl)cyanamide boiling at 130°-132° C. at 0.7 mm is collected.

Provenance & Evidence