3-Chloro-2-methylpropyl(dimethyl)ammonium chloride → 2-(2-Methyl-3-dimethylamino-propylamino)-5-chloropyrimidine

HRID 614324Notes

Reaction equation

HRID 614324 reaction equation
C([NH:4][C:5]1[N:10]=[CH:9][C:8]([Cl:11])=[CH:7][N:6]=1)(=O)C.Cl.[CH3:13][CH:14]([CH2:17][N:18]([CH3:20])[CH3:19])[CH2:15]Cl>>[CH3:13][CH:14]([CH2:17][N:18]([CH3:20])[CH3:19])[CH2:15][NH:4][C:5]1[N:10]=[CH:9][C:8]([Cl:11])=[CH:7][N:6]=1

Participants

3

Reactant 2

HCID 30838413-Chloro-2-methylpropyl(dimethyl)ammonium chlorideHCID 23349866N-(5-Chloropyrimidin-2-yl)acetamide

Product 1

HCID 233498932-(2-Methyl-3-dimethylamino-propylamino)-5-chloropyrimidine

Procedure

Following the procedure of Example 1 part A using 2-acetamido-5-chloropyrimidine and 2-methyl-3-dimethylaminopropyl chloride hydrochloride, there is obtained 2-(2-methyl-3-dimethylamino-propylamino)-5-chloropyrimidine.

Sources & evidence

ORD record
ord-dc12221d69214d639c1b850e5671d50e
Source dataset
uspto-grants-1979_03
Patent number
US04144338

Reaction notes

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