1-Chloro-2-dimethylamino-2-methylpropane hydrochloride → 2-(2-Methyl-2-dimethylaminopropylamino)-4-methyl-6-dimethylaminopyrimidine

HRID 614325Notes

Reaction equation

HRID 614325 reaction equation
C([NH:4][C:5]1[N:10]=[C:9]([CH3:11])[CH:8]=[C:7]([N:12]([CH3:14])[CH3:13])[N:6]=1)(=O)C.Cl.[CH3:16][C:17]([N:21]([CH3:23])[CH3:22])([CH3:20])[CH2:18]Cl>>[CH3:16][C:17]([N:21]([CH3:23])[CH3:22])([CH3:20])[CH2:18][NH:4][C:5]1[N:10]=[C:9]([CH3:11])[CH:8]=[C:7]([N:12]([CH3:13])[CH3:14])[N:6]=1

Participants

3

Reactant 2

HCID 227322711-Chloro-2-dimethylamino-2-methylpropane hydrochlorideHCID 233498782-Acetamido-4-methyl-6-dimethylaminopyrimidine

Product 1

HCID 233499052-(2-Methyl-2-dimethylaminopropylamino)-4-methyl-6-dimethylaminopyrimidine

Procedure

Following the procedure of Example 1 part A using 2-acetamido-4-methyl-6-dimethylaminopyrimidine and 2-methyl-2-dimethylaminopropyl chloride hydrochloride, there is obtained 2-(2-methyl-2-dimethylaminopropylamino)-4-methyl-6-dimethylaminopyrimidine.

Sources & evidence

ORD record
ord-f8dfa2dcadc84080b28d39a02983ba34
Source dataset
uspto-grants-1979_03
Patent number
US04144338

Reaction notes

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