Phosgene → HCID 12445574, compound

HRID 614334Notes

Reaction equation

HRID 614334 reaction equation
[NH2:1][C:2]1[C:3]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[C:10]=2[CH3:16])=[N:4][CH:5]=[CH:6][CH:7]=1.[C:17](Cl)(Cl)=[O:18]>>[Cl:15][C:11]1[C:10]([CH3:16])=[C:9]([N:8]2[C:3]3=[N:4][CH:5]=[CH:6][CH:7]=[C:2]3[NH:1][C:17]2=[O:18])[CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 6371PhosgeneHCID 12445424HCID 12445424, compound

Product 1

HCID 12445574HCID 12445574, compound

Procedure

The acid solution obtained in Step B was treated with phosgene as described in Example 1, Step C, to provide 3-(3-chloro-2-methylphenyl)-1,3-dihydroimidazo[4,5-b]pyridin-2-one, m.p. 224°-225° C.

Sources & evidence

ORD record
ord-d39dd5ab4cc94db0999bfb957454586b
Source dataset
uspto-grants-1979_03
Patent number
US04144341

Reaction notes

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