HCID 21816253, compound → 2,3-Dimethyl-1-benzofuran-5-amine

HRID 614337Notes

Reaction equation

HRID 614337 reaction equation
[CH3:1][C:2]1[O:3][C:4]2[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][C:5]=2[C:6]=1[CH3:7]>[Pd].CO>[CH3:1][C:2]1[O:3][C:4]2[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][C:5]=2[C:6]=1[CH3:7]

Participants

4

Reactant 1

HCID 21816253HCID 21816253, compound

Product 1

HCID 124453832,3-Dimethyl-1-benzofuran-5-amine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

2,3-Dimethyl-5-nitrobenzofuran (13.4 g.) was hydrogenated in 200 ml. of methanol over 0.6 g. of 5% palladium on carbon. The catalyst was removed by filtration and the filtrate was evaporated to dryness to give 2,3-dimethyl-5-aminobenzofuran, m.p. 77°-78° C.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-16612ecd9f744b21b3aeb474fba5af69
Source dataset
uspto-grants-1979_03
Patent number
US04144341

Reaction notes

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