反应详情

A suspension of 1.2 g. of 1,3-dihydro-3-(3,4-methylenedioxyphenyl)imidazo[4,5-b]pyridin-2-one in 75 ml. of dry dimethoxyethane was treated with 1 g. of n-butyl isocyanate and refluxed until solution was complete. The solution was filtered and evaporated to near dryness and diluted with petroleum ether. The precipitate was recrystallized from 30 ml. of ethanol by addition of water to give 400 mg. of 1,3-dihydro-3-(3,4-methylenedioxyphenyl)-2-oxoimidazo[4,5-b]pyridine-1-n-butylcarboxamide,. m.p. 129°-130° C.

1. additionA suspension of 1.2 g
2. filtrationThe solution was filtered
3. customevaporated
4. additiondiluted with petroleum ether
5. customThe precipitate was recrystallized from 30 ml
6. additionof ethanol by addition of water
7. customto give 400 mg