HCID 21329302, compound → HCID 21329310, compound

HRID 614350Notes

Reaction equation

HRID 614350 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[N:12]([CH2:13][CH:14]=[CH2:15])[C:11](=[O:16])[N:10]([C:17]3[CH:22]=[CH:21][C:20]4[O:23][CH2:24][O:25][C:19]=4[CH:18]=3)[C:7]2=[N:8][CH:9]=1)([O-])=O>[Pd].CO>[NH2:1][C:4]1[CH:5]=[C:6]2[N:12]([CH2:13][CH2:14][CH3:15])[C:11](=[O:16])[N:10]([C:17]3[CH:22]=[CH:21][C:20]4[O:23][CH2:24][O:25][C:19]=4[CH:18]=3)[C:7]2=[N:8][CH:9]=1

Participants

4

Reactant 1

HCID 21329302HCID 21329302, compound

Product 1

HCID 21329310HCID 21329310, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The nitro product of Step D, 340 mg. (0.001 mole), in 30 ml. of methanol was hydrogenated in the presence of 50 mg. of 5% palladium on carbon. The theoretical amount of hydrogen was absorbed. The catalyst was removed by filtration and the filtrate was evaporated to give the product which was crystallized from benzene by addition of hexane, m.p. 177°-178° C.

Workup

  1. customThe theoretical amount of hydrogen was absorbed
  2. customThe catalyst was removed by filtration
  3. customthe filtrate was evaporated
  4. customto give the product which
  5. customwas crystallized from benzene by addition of hexane, m.p. 177°-178° C.

Sources & evidence

ORD record
ord-31e9f31373ad45f69d18046566d01e15
Source dataset
uspto-grants-1979_03
Patent number
US04144341

Reaction notes

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