HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 2-bromo-2-methylpropionate → 2-(2-t-Butoxycarbonylprop-2-yloxyimino)-2-(thien-2-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 2-bromo-2-methylpropionate | HCID 90290 | — |
| Reactant | Benethamine(1+) | HCID 1549262 | — |
| Reactant | 2-Hydroxyimino(thien-2-yl)acetic acid | HCID 73629644 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(2-t-Butoxycarbonylprop-2-yloxyimino)-2-(thien-2-yl)acetic acid | HCID 54300039 | 78% |
Reaction Steps
The title compound was prepared from 2-hydroxyimino-2-(thien-2-yl)acetic acid (syn isomer) and t-butyl 2-bromo-2-methylpropionate, in a similar manner to that described for Preparation 1, in 78% yield as a colourless oil, and was characterised as the N-benzyl-2-phenylethylammonium salt, m.p. 201.3°-201.9° (from ethanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04144393 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-2f0fb51db1684aecb32016f21778516f |
| Source note | uspto-grants-1979_03 |