Cephapirin → HCID 70602996, compound

HRID 614446Notes

Reaction equation

HRID 614446 reaction equation
CC(O[CH2:5][C:6]1[CH2:25][S:24][C@@H:9]2[C@H:10]([NH:13][C:14]([CH2:16][S:17][C:18]3[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=3)=[O:15])[C:11](=[O:12])[N:8]2[C:7]=1[C:26]([OH:28])=[O:27])=O.[CH3:29][N:30]1[C:34]([SH:35])=[N:33][N:32]=[N:31]1>>[CH3:29][N:30]1[C:34]([S:35][CH2:5][C:6]2[CH2:25][S:24][C@@H:9]3[CH:10]([NH:13][C:14](=[O:15])[CH2:16][S:17][C:18]4[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=4)[C:11](=[O:12])[N:8]3[C:7]=2[C:26]([OH:28])=[O:27])=[N:33][N:32]=[N:31]1

Participants

3

Reactant 2

HCID 30699CephapirinHCID 178482017HCID 178482017, compound

Product 1

HCID 70602996HCID 70602996, compound

Procedure

7-(2-(4-pyridylthio)acetamido)cephalosporanic acid is reacted with 1-methyl-1H-tetrazole-5-thiol, yielding 3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-7-(2-(4-pyridylthio)acetamido)-3-cephem-4-carboxylic acid.

Sources & evidence

ORD record
ord-bbaeb621f71c4a9394458d0ef44a6af1
Source dataset
uspto-grants-1979_03
Patent number
US04144391

Reaction notes

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