反应详情

A mixture containing 10.0 g (0.312 mol) of methyl cis-1-(2,4-dimethoxybenzyl)-3-azido-4-oxoazetidine-2-carboxylate, 1.0 g of 10% palladium on carbon, and 200 ml of ethanol is hydrogenated for 2 hrs at 40°-45° at 60 psi of hydrogen. The reaction mixture is allowed to cool to 25° and is filtered through filter-aid. After removing the solvents in vacuo a clear, yellow gum of the title product is obtained.

1. temperatureto cool to 25°
2. filtrationis filtered
3. filtrationthrough filter-aid
4. customAfter removing the solvents in vacuo a clear, yellow gum of the title product
5. customis obtained