HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-oxopyrrolidine-1-acetate → N-[2-Methyl-2-(piperidin-1-yl)propyl]-2-(2-oxopyrrolidin-1-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-oxopyrrolidine-1-acetate | HCID 109094 | — |
| Reactant | 1-(2-Amino-1,1-dimethylethyl)piperidine | HCID 1713118 | — |
| Product | N-[2-Methyl-2-(piperidin-1-yl)propyl]-2-(2-oxopyrrolidin-1-yl)acetamide | HCID 44374414 | — |
Reaction Steps
From 8.56 g. of ethyl 2-oxo-1-pyrrolidineacetate and 12.5 g. of 2-methyl-2-(1-piperidinyl)propylamine [J.A.C.S. 68, 13 (1946)], following the procedure of Example 9, there is obtained N-[2-methyl-2-(1-piperidinyl)propyl]-2-oxo-1-pyrrolidineacetamide; m.p. 69° C. after crystallization from heptane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-7b7826809fbe4374b0c97127aaba5189 |
| Source note | uspto-grants-1979_03 |