HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-3-[2,6-Dimethylpiperidinyl]propylamine → cis-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-2,2-dimethyl-5-oxo-1-pyrrolidineacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-3-[2,6-Dimethylpiperidinyl]propylamine | HCID 7176132 | — |
| Reactant | Ethyl 2,2-dimethyl-5-oxopyrrolidineacetate | HCID 21327791 | — |
| Product | cis-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-2,2-dimethyl-5-oxo-1-pyrrolidineacetamide | HCID 70609594 | — |
Reaction Steps
From 10 g. of ethyl 2,2-dimethyl-5-oxopyrrolidineacetate, (British Pat. No. 1,309,692) and 10.5 g. of cis-3-(2,6-dimethyl-1-piperidinyl)propylamine, following the procedure of Example 9, there is obtained cis-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-2,2-dimethyl-5-oxo-1-pyrrolidineacetamide; m.p. 86°-87° C. after crystallization from isooctane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-ea65949aeb2a4b9e9902112d0ba12b29 |
| Source note | uspto-grants-1979_03 |