HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(cis-2,6-Dimethyl-1-piperidinyl)ethanamine → cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-oxo-4-phenyl-1-pyrrolidineacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(cis-2,6-Dimethyl-1-piperidinyl)ethanamine | HCID 783702 | — |
| Reactant | Methyl 2-oxo-4-phenyl-1-pyrrolidineacetate | HCID 13684993 | — |
| Product | cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-oxo-4-phenyl-1-pyrrolidineacetamide | HCID 70610073 | — |
Reaction Steps
From 7.0 g. of methyl 2-oxo-4-phenyl-1-pyrrolidineacetate and 5.0 g. of cis-2-(2,6-dimethyl-1-piperidinyl)-ethylamine, following the procedure of Example 9, there is obtained cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-oxo-4-phenyl-1-pyrrolidineacetamide; m.p. 115°-116° C. after recrystallization from cyclohexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-c5b3fe75e5f8451380a96f9ab6edf08f |
| Source note | uspto-grants-1979_03 |