HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-oxopyrrolidine-1-acetate → (+/-)-N-[2-(4-methyl-1-piperazinyl)propyl]-2-oxo-1-pyrrolidineacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-oxopyrrolidine-1-acetate | HCID 109094 | — |
| Reactant | 2-(4-Methylpiperazin-1-yl)propan-1-amine | HCID 16641457 | — |
| Product | (+/-)-N-[2-(4-methyl-1-piperazinyl)propyl]-2-oxo-1-pyrrolidineacetamide | HCID 21327809 | — |
Reaction Steps
From 7.0 g. of ethyl 2-oxo-1-pyrrolidineacetate and 6.3 g. of 2-(4-methyl-1-piperazinyl)propylamine, following the procedure of Example 9, there is obtained (±)-N-[2-(4-methyl-1-piperazinyl)propyl]-2-oxo-1-pyrrolidineacetamide; m.p. 84°-85° C. after recrystallization from cyclohexane and from heptane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-1d6feda2a2f540c69ff66a6f425f5c7a |
| Source note | uspto-grants-1979_03 |