HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester → 2-(2-methyl-5-oxo-1-pyrrolidinyl)-N-[2-(1-piperidinyl)propyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester | HCID 574476 | — |
| Reactant | 2-(Piperidin-1-yl)propan-1-amine | HCID 12455409 | — |
| Product | 2-(2-methyl-5-oxo-1-pyrrolidinyl)-N-[2-(1-piperidinyl)propyl]acetamide | HCID 21327783 | — |
Reaction Steps
From 9.3 g. of ethyl 2-methyl-5-oxo-1-pyrrolidineacetate and 10.7 g. of 2-(1-piperidinyl)propylamine (J. Chem. Soc. 1947, 1511), following the procedure of Example 9, there is obtained (±)-2-methyl-5-oxo-N-[2-(1-piperidinyl)propyl]-1-pyrrolidineacetamide; m.p. 111°-112° C. after recrystallization from heptane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145347 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-c5b7ab7d4a104f209d1703148255e20b |
| Source note | uspto-grants-1979_03 |