HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 3-(2-Aminobenzene-1-sulfonyl)-4-chlorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Chloro-3-(2-nitrobenzene-1-sulfonyl)benzoic acid | HCID 20384184 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(2-Aminobenzene-1-sulfonyl)-4-chlorobenzoic acid | HCID 20384182 | — |
Reaction Steps
A mixture of 4-chloro-3-(o-nitrophenylsulphonyl)benzoic acid (1.71g), stannous chloride (3.12g), concentrated hydrochloric acid (6.6 ml) and acetic acid (25 ml) was heated on the steamm bath for 30 min., cooled, and diluted with water. 3-(o-Aminophenylsulhonyl)-4-chlorobenzoic acid was filtered off, washed with water and dried, m.p. 235°-238° C, providing on recrystallisation from acetic acid, m.p. 246°-248° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145350 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-5fd8e2eb97a84220afc21a561ae21cee |
| Source note | uspto-grants-1979_03 |