Hydrochloric Acid → rac-(1R,2R)-2-(dimethylamino)cyclohexan-1-ol

Participants

Reaction Steps

This compound was previously prepared from cyclohexene oxide and dimethylamine in benzene at room temperature for 14 days in 95% yield, b.p. 90° (20 mm): J. Chem. Soc., 4835 (1965); or in autoclave: C.A. 67, 63899 d. Rocz. Chem. 41, 541 (1967) b.p. 88° (14 mm); also Bull. Soc. Chim. France, 850 (1947): hydrochloride and resolution reported.

Provenance & Evidence