HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-Acetoxy-5-naphthoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 5-Hydroxy-1-naphthoic acid | HCID 75531 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Acetoxy-5-naphthoic acid | HCID 458212 | — |
Reaction Steps
A solution of 20 g. of 5-hydroxy-1-naphthoic acid in 200 ml. of benzene and 40 ml. of acetyl chloride is refluxed for 3 hours. Solvent and excess acetyl chloride are evaporated. The mixture is dissolved in methanol (150 ml.) and water (20 ml.) added. After 15 minutes, addition of more water results in the precipitation of 1-acetoxy-5-naphthoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145443 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-1baa52067a1d454dbb10069acdf8461e |
| Source note | uspto-grants-1979_03 |