HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21328367, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-(Trifluoromethyl)benzaldehyde | HCID 67990 | — |
| Reactant | 2-[3-(Dimethylamino)propoxy]aniline | HCID 18672712 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 21328367 | HCID 21328367 | 52.6% |
Reaction Steps
A solution of 19.4g of 2-(3-dimethylaminopropoxy)aniline and 17.4g of m-trifluoromethylbenzaldehyde in 100ml of xylene is refluxed for about 6 hours. The water formed in the reaction is collected in a Dean-Stark tube. The solvent is removed under reduced pressure and the residue fractionated to yield 18.4g of the title compound as an oil, boiling point 155°-160° C. at 0.2-0.3 mm. of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145541 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-c0f891e7be5a43e28e0b21ba2381db1c |
| Source note | uspto-grants-1979_03 |