HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethoxymethane → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethoxymethane | HCID 8020 | — |
| Reactant | Ethyl 3-(3-hydroxyphenyl)propanoate | HCID 15197885 | — |
| Reactant | Ethyl 3-(3-chlorophenyl)propanoate | HCID 15209343 | — |
| Reactant | HCID 23346178 | HCID 23346178 | — |
| Reactant | HCID 23346189 | HCID 23346189 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 3053705 | HCID 3053705 | — |
Reaction Steps
Treatment of ethyl 3-(3-hydroxyphenyl)propionate with dimethoxymethane and substitution of the product for ethyl 3-(3-chlorophenyl)propionate in the procedure of Example 4 leads to the production of 5-[3-(methoxymethoxy)benzyl]-2-methylthio-4-pyrimidone and 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-[3-(methoxymethoxy)benzyl]-4-pyrimidone. Treatment of this product with hydrochloric acid gives 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-hydroxybenzyl)-4-pyrimidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145546 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-10762564ee644064a6a232acb795b2d1 |
| Source note | uspto-grants-1979_03 |