HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 4-Amino-2-hydroxymethyl-3-methoxypyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-Methoxy-2-methyl-4-nitropyridine 1-oxide | HCID 15163456 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 4-Amino-2-hydroxymethyl-3-methoxypyridine | HCID 20474201 | — |
Reaction Steps
4-Nitro-3-methoxy-2-methylpyridine N-oxide is heated in acetic anhydride and the purified product is deacetylated and reduced with hydrogen and palladium on charcoal to give 4-amino-2-hydroxymethyl-3-methoxypyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04145546 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-6a3b7e7edd5d4a1ea3cf15c4bebdd40e |
| Source note | uspto-grants-1979_03 |