HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-(dimethylamino)propyl)formamide → N,N-dimethyl-N-(5-nitro-2-methoxyphenyl)carbamylmethyl-N-3-formamidopropylammonium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-(dimethylamino)propyl)formamide | HCID 80020 | — |
| Reactant | 2-chloro-N-(2-methoxy-5-nitrophenyl)acetamide | HCID 2362603 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | N,N-dimethyl-N-(5-nitro-2-methoxyphenyl)carbamylmethyl-N-3-formamidopropylammonium chloride | HCID 86733013 | — |
Reaction Steps
In a manner similar to that described above in B-1a, and using 27.3 parts of N-(3-dimethylaminopropyl)formamide, 48 parts of 2-chloro-2'-methoxy-5'-nitroacetanilide, and 157 parts of isopropyl alcohol there was obtained 52.6 parts of N,N-dimethyl-N-(5-nitro-2-methoxyphenyl)carbamylmethyl-N-3-formamidopropylammonium chloride as a white solid, m.p. 86°-88°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04146558 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-b981329de3e24b6b91fbf392a09f3ecc |
| Source note | uspto-grants-1979_03 |