N-(2-Chloroethyl)-N-ethylaniline → N-methyl-N-2-(N'-ethylanilino)ethyl-N,N-bis(3-formamidopropyl)ammonium chloride

HRID 614730Notes

Reaction equation

HRID 614730 reaction equation
[CH:1]([NH:3][CH2:4][CH2:5][CH2:6][N:7]([CH3:14])[CH2:8][CH2:9][CH2:10][NH:11][CH:12]=[O:13])=[O:2].[CH2:15]([N:17]([CH2:24][CH2:25][Cl:26])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH3:16]>O>[Cl-:26].[CH3:14][N+:7]([CH2:16][CH2:15][N:17]([CH2:24][CH3:25])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)([CH2:6][CH2:5][CH2:4][NH:3][CH:1]=[O:2])[CH2:8][CH2:9][CH2:10][NH:11][CH:12]=[O:13]

Participants

4

Reactant 2

HCID 7093N-(2-Chloroethyl)-N-ethylanilineHCID 3084810Formamide, N,N'-[(methylimino)di-3,1-propanediyl]bis-

Product 1

HCID 86733018N-methyl-N-2-(N'-ethylanilino)ethyl-N,N-bis(3-formamidopropyl)ammonium chloride

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Proceeding in a manner similar to that described in C-1, 185.5 parts of N,N-bis(3-formamidopropyl)methylamine and 171 parts of N-ethyl-N-(2-chloroethyl)aniline were interacted in 140 parts of water to obtain a nearly quantitative yield of N-methyl-N-2-(N'-ethylanilino)ethyl-N,N-bis(3-formamidopropyl)ammonium chloride in the form of an aqueous solution.

Sources & evidence

ORD record
ord-d01fb330d505445697b8704e1c69dadf
Source dataset
uspto-grants-1979_03
Patent number
US04146558

Reaction notes

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