methyl N-(2-chloroacetyl)carbamate → 2-(Methoxycarbonylamino)-6-(2-pyridyloxy) imidazo [1,2-a] pyridine

HRID 614848Notes

Reaction equation

HRID 614848 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)=[CH:4][N:3]=1.Cl[CH2:16][C:17]([NH:19][C:20](=[O:23])[O:21][CH3:22])=O>>[CH3:22][O:21][C:20]([NH:19][C:17]1[N:1]=[C:2]2[CH:7]=[CH:6][C:5]([O:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=3)=[CH:4][N:3]2[CH:16]=1)=[O:23]

Participants

3

Reactant 2

HCID 518783methyl N-(2-chloroacetyl)carbamateHCID 544045145-(Pyridin-2-yloxy)pyridin-2-amine

Product 1

HCID 537616862-(Methoxycarbonylamino)-6-(2-pyridyloxy) imidazo [1,2-a] pyridine

Procedure

Reaction of 2-amino-5-(2-pyridyloxy) pyridine with methyl chloroacetylcarbamate as in Example 3 yields 2-(methoxycarbonylamino)-6-(2-pyridyloxy) imidazo [1,2-a] pyridine.

Sources & evidence

ORD record
ord-346ade9ac17d47339363e58c1018169d
Source dataset
uspto-grants-1979_03
Patent number
US04146642

Reaction notes

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