Carbamic acid, ethyl ester → HCID 21327523, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3.42 g of 2-(2-thenylamino)-5-nitrobenzhydrol, 6 g of ethyl carbamate and 0.5 g of zinc chloride was heated at 180° C. (bath temperature) for 2 hours. After cooling, the reaction mixture was dissolved in chloroform and the chloroform solution was washed with water and dried over anhydrous sodium sulfate. The solvent was removed under reduced pressure to give 1-(2-thenyl)-4-phenyl-6-nitro-3,4-dihydro-2(1H)-quinazolinone.

Provenance & Evidence