HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenylhydrazine sulfate → 3,5-Diphenyl-1-(p-chlorophenyl)-pyrazol-4-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenylhydrazine sulfate | HCID 112425 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 3,3-Dibenzoylpropionic acid ethyl ester | HCID 10852438 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3,5-Diphenyl-1-(p-chlorophenyl)-pyrazol-4-acetic acid | HCID 20542725 | 82.9% |
Reaction Steps
8.0 grams 3,3-dibenzoyl-propionic acid-ethyl ester, 5.9 grams p-chlorophenyl-hydrazine sulfate, 2.5 grams sodium acetate and 3.0 grams glacial acetic acid were reacted and the reaction product recovered by a procedure analogous to the method set out in Example (2a). 7.9 grams 3,5-diphenyl-1-(p-chlorophenyl)-pyrazol-4-acetic acid, melting at 193°-194° C. were obtained, representing a yield of 78%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04146721 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-78fcaa0540804f6394dd76609f10d231 |
| Source note | uspto-grants-1979_03 |