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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 615045Generated: October 30, 2026

Acetic Acid → 2-Acetoxy-3-hydroxypropyl 4-(n-hexadecylamino)benzoate

https://huagongshe.com/reaction/615045

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantWaterHCID 962—
Reactant2,3-Epoxypropyl 4-(n-hexadecylamino)benzoateHCID 13019377—
Product2-Acetoxy-3-hydroxypropyl 4-(n-hexadecylamino)benzoateHCID 44279627—

Reaction Conditions

Temperature100 °C

Reaction Steps

A mixture of 8.35 g of 2,3-epoxypropyl 4-(n-hexadecylamino)benzoate and 7.0 ml of acetic acid is heated at 100° C. for four hours, allowed to cool, and diluted with water. Filtration affords 2-acetoxy-3-hydroxypropyl 4-(n-hexadecylamino)benzoate, mp 67° C. unchanged by recrystallization.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04146546
Source datasetuspto-grants-1979_03
ORD IDord-b2e2592277194717a2af22efc86d7545
Source noteuspto-grants-1979_03