HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21326952, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | 1,1-Dihydroxypropan-2-one | HCID 13180982 | — |
| Reactant | 4-Hexadecylaminobenzoyl chloride hydrochloride | HCID 13255322 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 21326952 | HCID 21326952 | — |
Reaction Steps
The compound 4-(n-hexadecylamino)benzoyl chloride hydrochloride (4.16 g.) is added to a mixture of 3.6 g. of dihydroxyacetone and 2.44 g. of 4-dimethylaminopyridine in an ice bath. After 4 hours at room temperature, the mixture is treated with chloroform and water. The chloroform extract is chromatographed rapidly and evaporated in vacuo to yield 3-hydroxyacetonyl 4-(n-hexadecylamino)benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04146546 |
| Source dataset | uspto-grants-1979_03 |
| ORD ID | ord-5e77183b24054f38b47e1a8215fa160a |
| Source note | uspto-grants-1979_03 |