HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formamide → 3,7-Dichloro-8-formylaminomethylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | HCID 13090784 | HCID 13090784 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3,7-Dichloro-8-formylaminomethylquinoline | HCID 13090794 | — |
Reaction Steps
24.6 parts of 3,7-dichloro-8-chloromethylquinoline (Example 1) in 300 parts of formamide were refluxed for 5 hours. Water was added and the solid was filtered off with suction and recrystallized from methanol. 23 parts of 3,7-dichloro-8-formylaminomethylquinoline of melting point 110° C. were obtained. The yield corresponds to 94% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04497651 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-34994bb00d9f4ed78e4b0d34a151a011 |
| Source note | uspto-grants-1985_02 |