反应详情

2-Amino-5,6-dimethylbenzimidazole monohydrate, acetone and methyl isocyanate were reacted, conducting the initial condensation and subsequent base hydrolysis of the intermediate 10-N-methylcarbamoyl precursor as described in Example 1. The title compound was recovered and purified by liquid chromatography to give a solid, mp 211° C. (dec.). The confirmatory elemental analysis is shown in Table III.

1. customcondensation and subsequent base hydrolysis of the intermediate 10-N-methylcarbamoyl precursor
2. customThe title compound was recovered
3. custompurified by liquid chromatography
4. customto give a solid, mp 211° C. (dec.)